MED 310 | Course Introduction and Application Information

Course Name
Current Topics in Immunology and Cancer
Code
Semester
Theory
(hour/week)
Application/Lab
(hour/week)
Local Credits
ECTS
MED 310
Fall/Spring
3
0
3
5

Prerequisites
None
Course Language
English
Course Type
Elective
Course Level
First Cycle
Mode of Delivery -
Teaching Methods and Techniques of the Course Discussion
Group Work
Jury
Lecture / Presentation
Course Coordinator
Course Lecturer(s)
Assistant(s) -
Course Objectives This course aims to inform students about the latest topics in immunology by focusing on cancer.
Learning Outcomes The students who succeeded in this course;
  • 1. Define the concepts and terms about immunology and cancer.
  • 2. Describe the cells and tissues of the immune system with their functions.
  • 3.Explain antigen presentation mechanisms associated with cancer.
  • 4.Explain natural, acquired and mucosal immunity.
  • 5.Explain immunology of transplantation, immune tolerance, autoimmunity and immune regulation concepts and relation to disorders.
  • 6. Describe “Tumor Antigens” and “Tumor Associated Antigens”
  • 7. Explain examples of cancer-specific immune responses and how tumors avoid these responses.
  • 8. Describe approaches for using immune responses for cancer treatment.
Course Description This course begins with a general introduction to the mechanism of antigen delivery, which is a summary of the innate and adaptive immune system and complement system, which aims to cover the functioning of the immune system cells and tissues and then the basic mechanisms of the immune system as a whole. The course will focus on the main mechanisms of tumor immune response.

 



Course Category

Core Courses
Major Area Courses
Supportive Courses
X
Media and Management Skills Courses
Transferable Skill Courses

 

WEEKLY SUBJECTS AND RELATED PREPARATION STUDIES

Week Subjects Related Preparation
1 Introduction to the Immune system: Cells and Tissues of the Immune System Cellular and Molecular Immunology 10th Ed. Abul K. Abbas MBBS, Andrew H. Lichtman MD, PhD and Shiv Pillai MBBS, PhD Chapter 1, 1-11 Chapter 2, 13-41
2 Antigen Presentation to T Lymphocytes and the Function of Major Histocompatibility Complex Molecules Cellular and Molecular Immunology 10th Ed. Abul K. Abbas MBBS, Andrew H. Lichtman MD, PhD and Shiv Pillai MBBS, PhD Chapter 6, 123-150
3 Innate Immune System Cellular and Molecular Immunology 10th Ed. Abul K. Abbas MBBS, Andrew H. Lichtman MD, PhD and Shiv Pillai MBBS, PhD Chapter 4, 63-102
4 Activation of T lymphocytes, Differentiation and Function of CD4 and CD8 T Cells Cellular and Molecular Immunology 10th Ed. Abul K. Abbas MBBS, Andrew H. Lichtman MD, PhD and Shiv Pillai MBBS, PhD Chapter 9, 217-232 Chapter 10, 233-250 Chapter 11, 251-259
5 B Cell Activation and Antibody production Cellular and Molecular Immunology 10th Ed. Abul K. Abbas MBBS, Andrew H. Lichtman MD, PhD and Shiv Pillai MBBS, PhD Chapter 12, 261-285
6 Specialized Immunity at Epithelial Barriers and in Immune Privileged Tissues Cellular and Molecular Immunology 10th Ed. Abul K. Abbas MBBS, Andrew H. Lichtman MD, PhD and Shiv Pillai MBBS, PhD Chapter 14, 313-336
7 Transplantation Immunology Cellular and Molecular Immunology 10th Ed. Abul K. Abbas MBBS, Andrew H. Lichtman MD, PhD and Shiv Pillai MBBS, PhD Chapter 17, 389-413
8 Immune Tolerance and Autoimmunity Cellular and Molecular Immunology 10th Ed. Abul K. Abbas MBBS, Andrew H. Lichtman MD, PhD and Shiv Pillai MBBS, PhD Chapter 15, 337-363
9 Immune Regulation Cellular and Molecular Immunology 10th Ed. Abul K. Abbas MBBS, Andrew H. Lichtman MD, PhD and Shiv Pillai MBBS, PhD Chapter 9 and 15 p 211-213, 315-339
10 Tumor Antigens Cellular and Molecular Immunology 10th Ed. Abul K. Abbas MBBS, Andrew H. Lichtman MD, PhD and Shiv Pillai MBBS, PhD Chapter 18 Tumor Immunology 415-436 www.clinicalkey.com
11 Tumor Immune Responses Cellular and Molecular Immunology 10th Ed. Abul K. Abbas MBBS, Andrew H. Lichtman MD, PhD and Shiv Pillai MBBS, PhD Chapter 18 Tumor Immunology 415-436 www.clinicalkey.com
12 Evasion of Immune Responses by Tumors Cellular and Molecular Immunology 10th Ed. Abul K. Abbas MBBS, Andrew H. Lichtman MD, PhD and Shiv Pillai MBBS, PhD Chapter 18 Tumor Immunology 415-436 www.clinicalkey.com
13 Immunotherapy for Tumors I: Passive Immunotherapy and Adoptive T Cell Therapy Cellular and Molecular Immunology 10th Ed. Abul K. Abbas MBBS, Andrew H. Lichtman MD, PhD and Shiv Pillai MBBS, PhD Chapter 18 Tumor Immunology 415-436 www.clinicalkey.com
14 Immunotherapy for Tumors II: Immune Checkpoint Blockade and Tumor Antigen Vaccination Cellular and Molecular Immunology 10th Ed. Abul K. Abbas MBBS, Andrew H. Lichtman MD, PhD and Shiv Pillai MBBS, PhD Chapter 18 Tumor Immunology 415-436 www.clinicalkey.com
15 Semester Review
16 Final Exam

 

Course Notes/Textbooks

Cellular and Molecular Immunology 10th Ed.  Abul K. Abbas MBBS, Andrew H. Lichtman MD, PhD and Shiv Pillai MBBS, PhD

 

Access through www.clinicalkey.com

Suggested Readings/Materials

 

EVALUATION SYSTEM

Semester Activities Number Weigthing
Participation
1
10
Laboratory / Application
Field Work
Quizzes / Studio Critiques
Portfolio
Homework / Assignments
1
20
Presentation / Jury
1
30
Project
Seminar / Workshop
Oral Exams
Midterm
Final Exam
1
40
Total

Weighting of Semester Activities on the Final Grade
3
60
Weighting of End-of-Semester Activities on the Final Grade
1
40
Total

ECTS / WORKLOAD TABLE

Semester Activities Number Duration (Hours) Workload
Theoretical Course Hours
(Including exam week: 16 x total hours)
16
3
48
Laboratory / Application Hours
(Including exam week: '.16.' x total hours)
16
0
Study Hours Out of Class
14
2
28
Field Work
0
Quizzes / Studio Critiques
0
Portfolio
0
Homework / Assignments
1
15
15
Presentation / Jury
1
25
25
Project
0
Seminar / Workshop
0
Oral Exam
0
Midterms
0
Final Exam
1
29
29
    Total
145

 

COURSE LEARNING OUTCOMES AND PROGRAM QUALIFICATIONS RELATIONSHIP

#
Program Competencies/Outcomes
* Contribution Level
1
2
3
4
5
1

Knowledge for Practice: Uses knowledge in biomedical, clinical, epidemiological, biostatistics, biomedical informatics, social and behavioral sciences for the prevention, diagnosis, treatment and management of medical problems.

X
2

Information Management and Research: Uses the information generated through research and accessed from different sources in evidence-based patient management processes

X
3

Patient management: Provides patient-centered, holistic, safe, reliable and evidence-based health care for common health problems in the community, prioritizing health protection and improvement*.

4

Patient and employee safety: Provides health services by considering the health and safety of patients and employees.

5

Protection and promotion of health: Prioritizes protecting and improving the health of individuals and society in the provision of health services under usual/unusual situations. Performs clinical and public health practices in a holistic and competent manner

6

Adherence to ethical principles: Fulfills the duties and obligations within the framework of ethical principles and, rights and legal responsibilities required by the profession.

7

Professional competence: Provides a high-quality healthcare service that prioritizes patient safety. While applying the profession, he/she knows his/her limits, evaluates his/her own performance, determines the aspects that need to be developed and improves them within a plan

8

Professional virtues: Avoid behaviors that will undermine the public's trust in medicine. S/he approaches her/his patients with compassion and care without discrimination, and puts their welfare ahead of her/his own interests

9

A healthy physician- a healthy society: Gives importance to his/her personal health, safety and appearance, sets an example for his/her colleagues and society by taking the necessary precautions.

10

Planetary health and healthy lifestyles: Considering the effects of the resources offered by our planet on individual and public health, he/she accepts promoting healthy lifestyles and eliminating the factors that negatively affect health his/her duty.

11

Protecting and improving health as a social responsibility: Accepts protection and improvement of public health as a social responsibility, identifies the primary health problems of the society served and produces solutions.

12

Health policies: Evaluates the impact of health policies on the health indicators of individuals and society, and advocates increasing the quality of health services.

13

Change management: Systematically identifies and manages the issues/processes and the necessary resources that require change in order to provide quality, safe and cost-effective health care.

14

Personal qualifications: Provides evidence exerting that he/she is equipped enough to lead changes to make healthcare more qualified, safe and cost-effective

15

Communication skills: Uses verbal and non-verbal communication effectively. Communicates with patients in a way that makes them feel understood, with active listening behaviors (eye contact, affirmation, summarizing, etc.)

X
16

Communication with patients and their relatives: Establishes supportive relationships with patients and their families that contribute positively to the treatment process

17

Communication for qualified and safe health care: Communicates with patients, their relatives, health workers, other professional groups, institutions and organizations in a clear, understandable and professional manner that will minimize patient safety risks and increase the quality of health care. Considers and protects patient privacy and data security in all communications.

18

Explains the place and importance of scientific research and evidence in providing qualified and safe health care. Analyzes the health problems in the society s/he serves with scientific methods. Reaches information to access evidence. Uses the information analyzed and the evidence accessed from the literature to provide more qualified and safer health care

X
19

Reflection: Using reflective approaches, he/she questions his/her professional performance, identifies areas that require improvement, and develops his/her professional knowledge and skills by identifying learning needs.

20

Stress management: Explains and applies strategies for coping with stress and preventing burnout

*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest

 


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