MED 260 | Course Introduction and Application Information

Course Name
Introduction to Immunology
Code
Semester
Theory
(hour/week)
Application/Lab
(hour/week)
Local Credits
ECTS
MED 260
Fall/Spring
3
0
3
4

Prerequisites
None
Course Language
English
Course Type
Elective
Course Level
First Cycle
Mode of Delivery -
Teaching Methods and Techniques of the Course -
Course Coordinator
Course Lecturer(s) -
Assistant(s) -
Course Objectives This course aims to train the students with an introductory level in immunology.
Learning Outcomes The students who succeeded in this course;
  • 1-Define basic immunology concepts and terms.
  • 2-Describe the cells, tissues and organs related to immunology.
  • 3-Specify the stages of immune response and signs of inflammation.
  • 4-Explain natural and acquired immunity, related cells and antigen presentation.
  • 5-Classify the main disease groups associated with the dysregulation of the immune system.
  • 6-Explain examples of cancer-specific immune responses and their use in cancer treatment.
Course Description This course begins with a general introduction to how immune system cells and tissues work, followed by the development and migration of these cells under physiological conditions. The course will continue with the stages of immune response and inflammation under pathological conditions, and will focus on the basic mechanisms of immune responses.

 



Course Category

Core Courses
Major Area Courses
Supportive Courses
X
Media and Management Skills Courses
Transferable Skill Courses

 

WEEKLY SUBJECTS AND RELATED PREPARATION STUDIES

Week Subjects Related Preparation
1 Introduction Examination of the posted syllabus, requirements and course flow
2 Immune system Cells and Tissues: Myeloid vs. Lymphoid Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 8th Edition Chapter 1 and 2 p 1-35
3 Development and Migration of Leukocytes Janeway C. and Medzhitov R. Immunobiology 8th Ed. Ch. 1
4 Phases of an Immune response and Inflammation Sherris Medical Microbiology Kenneth C. Ryan Chapter 2: Immune response to Infection. Innate (Natural) Immunity (Access Medicine- no page numbers)
5 Innate immune system: Mucosal Immunity and Microbiota “The human skin microbiome” Nature Reviews Microbiology 16, pages 143–155 (2018) doi:10.1038/nrmicro.2017.157 Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 8th Edition Chapter 14 p 289
6 Innate immune system: Phagocytosis and Complement system Jawetz Medical Microbiology Chapter 8: Immunity: Mechanisms of Innate Immunity: Innate (Natural) Immunity D. Complement System (Access Medicine- no page numbers)
7 Antigens and Antigen presentation Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 8th Edition Chapter 6 p 117-145
8 T lymphocytes and activation Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 8th Edition Chapter 8, 9, 10 and11 p 171-239
9 B lymphocytes and activation, antibody production and function Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 8th Edition Chapter 8, 12 and 13 p 239-289
10 Tolerance and Autoimmunity: Case study Review of Medical Microbiology & Immunology: A Guide to Clinical Infectious Diseases, 16e Chap 38: Respiratory viruses
11 Hypersensitivity and Allergy Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 8th Edition Chapter 19-20 p 417-437
12 Immunodeficiencies and Transplantation Immunology Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 8th Edition Chapter 17-21 p 373/459
13 Tumor Immunology and Immunotherapy of Cancer Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 8th Edition Chapter 18 p 397-417 Lisa Butterfield, Howard Kaufmann, F. Marincola Cancer Immunotherapy Principles and Practice, Section II: Cancer Immunothrapy Targets and Classes 231-404
14 Immunotherapy of Cancer Lisa Butterfield, Howard Kaufmann, F. Marincola Cancer Immunotherapy Principles and Practice, Section II: Cancer Immunothrapy Targets and Classes 231-404
15 Poster presentations and Semester Review
16 Final Exam

 

Course Notes/Textbooks

Lisa Butterfield, Howard Kaufmann, F. Marincola Cancer Immunotherapy ISBN 9781620700976

Abul K Abbas, Andrew H Lichtman, Shiv Pillai, “Cellular and Molecular Immunology” 8th Edition ISBN 978-0 323-52324-0

Karren C Carroll, Jawetz, Melnick, & Adelberg’s Medical Microbiology, 27e 2018 ISBN 9780-0-71-82498-9

Kenneth J Ryan, Sherris Medical Microbiology 7th ed. 2018 ISBN 978-1-259-85980-9

Charles Janeway and Ruslan Medzhitov “Immunobiology” 9th Ed. ISBN 978-0815345848

Suggested Readings/Materials

Access Medicine online access to  Jawetz Medical Microbiology

Sherris Medical Microbiology will be provided by the Faculty of Medicine online acccess

Abul K Abbas, Andrew H Lichtman, Shiv Pillai, Cellular and Molecular Immunology 8th Edition is available through IEU library

Notes from Lisa Butterfield, Howard Kaufmann, F. Marincola Cancer Immunotherapy Principles and Practice will be provided during the course

 

EVALUATION SYSTEM

Semester Activities Number Weigthing
Participation
1
10
Laboratory / Application
Field Work
Quizzes / Studio Critiques
Portfolio
Homework / Assignments
1
10
Presentation / Jury
1
40
Project
Seminar / Workshop
Oral Exams
Midterm
Final Exam
1
40
Total

Weighting of Semester Activities on the Final Grade
3
60
Weighting of End-of-Semester Activities on the Final Grade
1
40
Total

ECTS / WORKLOAD TABLE

Semester Activities Number Duration (Hours) Workload
Theoretical Course Hours
(Including exam week: 16 x total hours)
16
3
48
Laboratory / Application Hours
(Including exam week: '.16.' x total hours)
16
0
Study Hours Out of Class
15
2
30
Field Work
0
Quizzes / Studio Critiques
0
Portfolio
0
Homework / Assignments
1
10
10
Presentation / Jury
1
10
10
Project
0
Seminar / Workshop
0
Oral Exam
0
Midterms
0
Final Exam
1
22
22
    Total
120

 

COURSE LEARNING OUTCOMES AND PROGRAM QUALIFICATIONS RELATIONSHIP

#
Program Competencies/Outcomes
* Contribution Level
1
2
3
4
5
1

Knowledge for Practice: Uses knowledge in biomedical, clinical, epidemiological, biostatistics, biomedical informatics, social and behavioral sciences for the prevention, diagnosis, treatment and management of medical problems.

X
2

Information Management and Research: Uses the information generated through research and accessed from different sources in evidence-based patient management processes

3

Patient management: Provides patient-centered, holistic, safe, reliable and evidence-based health care for common health problems in the community, prioritizing health protection and improvement*.

4

Patient and employee safety: Provides health services by considering the health and safety of patients and employees.

5

Protection and promotion of health: Prioritizes protecting and improving the health of individuals and society in the provision of health services under usual/unusual situations. Performs clinical and public health practices in a holistic and competent manner

6

Adherence to ethical principles: Fulfills the duties and obligations within the framework of ethical principles and, rights and legal responsibilities required by the profession.

7

Professional competence: Provides a high-quality healthcare service that prioritizes patient safety. While applying the profession, he/she knows his/her limits, evaluates his/her own performance, determines the aspects that need to be developed and improves them within a plan

8

Professional virtues: Avoid behaviors that will undermine the public's trust in medicine. S/he approaches her/his patients with compassion and care without discrimination, and puts their welfare ahead of her/his own interests

9

A healthy physician- a healthy society: Gives importance to his/her personal health, safety and appearance, sets an example for his/her colleagues and society by taking the necessary precautions.

10

Planetary health and healthy lifestyles: Considering the effects of the resources offered by our planet on individual and public health, he/she accepts promoting healthy lifestyles and eliminating the factors that negatively affect health his/her duty.

X
11

Protecting and improving health as a social responsibility: Accepts protection and improvement of public health as a social responsibility, identifies the primary health problems of the society served and produces solutions.

X
12

Health policies: Evaluates the impact of health policies on the health indicators of individuals and society, and advocates increasing the quality of health services.

13

Change management: Systematically identifies and manages the issues/processes and the necessary resources that require change in order to provide quality, safe and cost-effective health care.

14

Personal qualifications: Provides evidence exerting that he/she is equipped enough to lead changes to make healthcare more qualified, safe and cost-effective

15

Communication skills: Uses verbal and non-verbal communication effectively. Communicates with patients in a way that makes them feel understood, with active listening behaviors (eye contact, affirmation, summarizing, etc.)

16

Communication with patients and their relatives: Establishes supportive relationships with patients and their families that contribute positively to the treatment process

17

Communication for qualified and safe health care: Communicates with patients, their relatives, health workers, other professional groups, institutions and organizations in a clear, understandable and professional manner that will minimize patient safety risks and increase the quality of health care. Considers and protects patient privacy and data security in all communications.

18

Explains the place and importance of scientific research and evidence in providing qualified and safe health care. Analyzes the health problems in the society s/he serves with scientific methods. Reaches information to access evidence. Uses the information analyzed and the evidence accessed from the literature to provide more qualified and safer health care

19

Reflection: Using reflective approaches, he/she questions his/her professional performance, identifies areas that require improvement, and develops his/her professional knowledge and skills by identifying learning needs.

20

Stress management: Explains and applies strategies for coping with stress and preventing burnout

*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest

 


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