CCS 403 | Course Introduction and Application Information

Course Name
Internal Medicine
Code
Semester
Theory
(hour/week)
Application/Lab
(hour/week)
Local Credits
ECTS
CCS 403
Fall/Spring
14
16
13
13

Prerequisites
None
Course Language
English
Course Type
Required
Course Level
First Cycle
Mode of Delivery -
Teaching Methods and Techniques of the Course Case Study
Q&A
Application: Experiment / Laboratory / Workshop
Lecture / Presentation
Course Coordinator
Course Lecturer(s)
Assistant(s) -
Course Objectives It is aimed that the students will acquire the ability to use the clinical reasoning approach in the diagnosis and treatment of the diseases within the scope of this clerkship (internal medicine, hematology, rheumatology, gastroenterology, endocrinology, nephrology, oncology and allergy-immunology). Protection from these diseases will be addressed within the perspectives of lifestyle medicine at the individual level, socially oriented health (SOH) at the community level, and planetary health / public health at the health systems / policies level.
Learning Outcomes The students who succeeded in this course;
  • 1. Explain the basic principles and approaches in the epidemiology, clinics, diagnosis and management of diseases that are frequently encountered in primary care.
  • 2. Access to reliable sources of information about clinical situations / problems, use evidence-based medical tools to evaluate the information accessed, and correlate the obtained information with the patient's condition.
  • 3. Perform appropriate and guided history taking and physical examination from patients in accordance with appropriate communication principles.
  • 4. Establish ranked differential diagnosis for patients presented with the symptoms assigned for this clerkship.
  • 5. Evaluate the effectiveness, cost-effectiveness, potential early and late side effects of the diagnostic methods, and their suitability for differential diagnosis with an evidence-based manner.
  • 6. Differentiate emergent and non-urgent situations.
  • 7. Demonstrate knowledge and skills to apply and interpret determined minor medical interventions and applications.
  • 8. Determine pharmacological and non-pharmacological treatment options for the patients in clinical and emergency situations with an evidence-based medical approach.
  • 9. Do risk assessment and take precautions.
  • 10. Make management plans for the patients according to bioethical principles and legal responsibilities of physicians.
  • 11. Identify the need for consultation and indications for referrals when necessary by distinguishing the diseases that require special expertise.
  • 12. Explain health events at individual, social and ecosystem levels via social determinants of health perspective, and shows exemplary behaviors appropriate to this point of view in her/his personal life.
  • 13. Define the target population, method and implementation strategies of control, screening and immunization programs for health protection and disease prevention.
  • 14. Define the risk factors and social determinants of common diseases in the context of the patient, and create evidence-based prevention / solution recommendations for them.
  • 15. Contribute to the work of the team as an effective member s/he take part in.
  • 16. Establish an open, constructive and respectful communication with the people s/he work with.
  • 17. Establish an open, constructive and respectful communication with patients and patients' relatives by using appropriate language.
  • 18. Create accurate and reasonable patient records that has secured, verbally present the patient, and hand over patients safely and effectively.
  • 19. Use reflective approaches to identify and improve his/her professional performance.
Course Description In this course, the diagnosis, differential diagnosis, management and prevention methods of common diseases and emergencies in gastroenterology, endocrinology, hematology, oncology, nephrology, rheumatology and allergy-immunology will be discussed.

 



Course Category

Core Courses
Major Area Courses
X
Supportive Courses
Media and Management Skills Courses
Transferable Skill Courses

 

WEEKLY SUBJECTS AND RELATED PREPARATION STUDIES

Week Subjects Related Preparation
1 HEMATOLOGY General evaluation and physical examination of the hematological patient. Approach to the patient with LAP. Approach to the patient with anemia. Approach to the patient with leukocytosis and leukopenia. Approach to patients with bleeding disorders. Hypercoagulability. Blood transfusion principles. RHEUMATOLOGY Overview of rheumatological diseases and approach to locomotor system pain. Diagnostic tests in rheumatic diseases and treatment. Connective tissue diseases. 1.Monogenic autoinflammatory diseases:Adriana A. de Jesus, Michael F. McDermott, Daniel L. Kastner and Raphaela Goldbach-ManskyRHEUMATOLOGY, 7th edition ISBN: 978-0-7020-6865-2 2.Familial Mediterranean Fever.Ozdogan H, Ugurlu S.Presse Med. 2019 Feb;48 review. 3.Clinical features of spondyloarthritis : Imaging of spondyloarthritis. Management of axial spondyloarthritis : .Clinical features of psoriatic arthritis. Hochberg, Marc C., MD, MPH, MACP, MACR RHEUMATOLOGY, 7th edition ISBN: 978-0-7020-6865-2 4.Peripheral spondyloarthritis: Concept, diagnosis and treatment.Molto A, Sieper J.Best Pract Res Clin Rheumatol. 2018 Jun;32(3):357-368 5.EULAR recommendations for the use of imaging in the diagnosis and management of spondyloarthritis in clinical practice.Mandl P, Navarro-Compán V, Terslev L, Aegerter P, van der Heijde D, D'Agostino MA, Baraliakos X, Pedersen SJ, et al. European League Against Rheumatism (EULAR).Ann Rheum Dis. 2015 Jul;74 6. Management of gout and hyperuricemia : .Calcium pyrophosphate deposition disease (pseudogout).Hochberg, Marc C., RHEUMATOLOGY, 7th edition ISBN: 978-0-7020-6865-. 7.Gout .An update of aetiology, genetics, co-morbidities and management.Robinson PC.Maturitas. 2018 Dec; 118:67. 8.Update on the epidemiology, risk factors, and disease outcomes of rheumatoid arthritis.Diane van der Woude and Annette H.M. van der Helm-van Mil Best Practice & Research: Clinical Rheumatology, 2018-04-01, Volume 32. 9.CLINICAL OVERVIEW Systemic lupus erythematosusElsevier Point of Care.Updated August 29, 2020. Copyright Elsevier. 10.Sjogren’s syndrome: An update on disease pathogenesis, clinical manifestations and treatmentFrederick B. Vivino, Vatinee Y. Bunya, Giacomina Massaro-Giordano, Chadwick R. Johr, Stephanie L. Giattino, Annemarie Schorpion, Brian Shafer. Clinical Immunology, 2019-06-01, Volume 203.
2 HEMATOLOGY Acute and chronic leukemia. B and T cell lyphomas. Plasma cell disease. Bone marrow failure. Hematopoietic Stem cell transplantation. Myelodysplastic syndrome. Chronic Myeloproliferative Diseases. RHEUMATOLOGY Vasculitis and Behçet's Disease-1. Vasculitis and Behçet's Disease-2. Polimyalgia Rheumatica. Gout disease. Familial Mediterranean Fever. Spondyloarthritis. 1. Classification and epidemiology of vasculitis Richard A. Wattsand Eleana Ntatsaki. Biology and immunopathogenesis of vasculitis, Polyarteritis nodosa and Cogan syndrome, Antineutrophil cytoplasm antibody–associated vasculitis, Takayasu arteritis, Cutaneous vasculitis and panniculitis.Hochberg, Marc C., MD, RHEUMATOLOGY, 7th edition ISBN: 978-0-7020-6865-2 2.Best Pract Res Clin Rheumatol 2018 Apr;32(2):261-270 Update on the epidemiology, risk factors and disease outcomes of Beh軻t's disease . Nurullah Akko. 3.Best Pract Res Clin Rheumatol 2018 Feb;32(1):3-20.Introduction, epidemiology and classification of vasculitis Richard A Watts 1, Joanna Robson. 4.Nat Rev Rheumatol 2017 Oct;13(10):578-592. Giant cell arteritis and polymyalgia rheumatica: current challenges and opportunities Christian Dejaco, Elisabeth Brouwer , Justin C Mason, Frank Buttgereit, Eric L Matteson, Bhaskar Dasgupta.
3 GASTROENTEROLOGY Approach to the patient with diarrhea-1. Approach to the patient with diarrhea-2. Liver diseases-1. Liver diseases-2. Approach to the patient presenting with nausea and vomiting-Clinical Nutrition. Approach to patients with gastrointestinal complaints. Stomach diseases. Esophageal diseases. Approach to the patient presenting withgastrointestinal bleeding-1. Approach to the patient presenting with gastrointestinal bleeding-2. Approach to the patient presenting with abdominal pain-1. Approach to the patient presenting with abdominal pain-2. 1.Ghany MG, Hoofnagle JH. Approach to the Patient with Liver Disease. In: Jameson J, Fauci AS, Kasper DL, Hauser SL, Longo DL, Loscalzo J. eds. Harrison's Principles of Internal Medicine, 20e. McGraw-Hill; 2018,329. 2.Pratt DS. Evaluation of Liver Function. In: Jameson J, Fauci AS, Kasper DL, Hauser SL, Longo DL, Loscalzo J. eds. Harrison's Principles of Internal Medicine, 20e. McGraw-Hill; 2018,330. 3.Wolkoff AW. The Hyperbilirubinemias. In: Jameson J, Fauci AS, Kasper DL, Hauser SL, Longo DL, Loscalzo J. eds. Harrison's Principles of Internal Medicine, 20e. McGraw-Hill;2018,331. 4.Dienstag JL. Acute Viral Hepatitis. In: Jameson J, Fauci AS, Kasper DL, Hauser SL, Longo DL, Loscalzo J. eds. Harrison's Principles of Internal Medicine, 20e. McGraw-Hill;2018,332. 5.Lee WM, Dienstag JL. Toxic and Drug-Induced Hepatitis. In: Jameson J, Fauci AS, Kasper DL, Hauser SL, Longo DL, Loscalzo J. eds. Harrison's Principles of Internal Medicine, 20e. McGraw-Hill; 2018,333. 6.Dienstag JL. Chronic Hepatitis. In: Jameson J, Fauci AS, Kasper DL, Hauser SL, Longo DL, Loscalzo J. eds. Harrison's Principles of Internal Medicine, 20e. McGraw-Hill;2018,334. 7.Mailliard ME, Sorrell MF. Alcoholic Liver Disease. In: Jameson J, Fauci AS, Kasper DL, Hauser SL, Longo DL, Loscalzo J. eds. Harrison's Principles of Internal Medicine, 20e. McGraw-Hill; 2018,335. 8.Abdelmalek MF, Diehl A. Nonalcoholic Fatty Liver Diseases. and Nonalcoholic Steatohepatitis. In: Jameson J, Fauci AS, Kasper DL, Hauser SL, Longo DL, Loscalzo J. eds. Harrison's Principles of Internal Medicine, 20e. McGraw-Hill;2018,336. 9.Bacon BR. Cirrhosis and Its Complications. In: Jameson J, Fauci AS, Kasper DL, Hauser SL, Longo DL, Loscalzo J. eds. Harrison's Principles of Internal Medicine, 20e. McGraw-Hill;2018,337. 10.Binder HJ. Disorders of Absorption. In: Jameson J, Fauci AS, Kasper DL, Hauser SL, Longo DL, Loscalzo J. eds. Harrison's Principles of Internal Medicine, 20e. McGraw-Hill;2018, 318. 11.Friedman S, Blumberg RS. Inflammatory Bowel Disease. In: Jameson J, Fauci AS, Kasper DL, Hauser SL, Longo DL, Loscalzo J. eds. Harrison's Principles of Internal Medicine, 20e. McGraw-Hill;2018,319.
4 ALLERGY and IMMUNOLOGY Approach to the Patient with Allergic or Immunologic Disease. Systemic Anaphylaxis. Urticaria and Angioedema. Food and Drug Allergy. ENDOCRINOLOGY and METABOLIC DISORDERS Approach in endocrinological diseases. Adult gonadal diseases. Polycystic ovary syndrome. Endocrinology and hypertension. Thyroiditis, thyroid nodules and thyroid neoplasms. Endocrinologic disorders in pregnancy. Anterior pituitary and hypothalamus diseases. Hyperthyroidism. Osteoporosis- osteomalacia. Diabetes Mellitus. DM complications and treatment. Obesity. Diabetes insipidus and inappropriate ADH syndrome. Hypo-hypercalcemia. Diabetic Emergencies. Adrenal gland diseases. 1.Nadeau KC. Approach to the patient with allergic or immunologic disease. In: Goldman L, Schafer Andrew I, eds. Goldman-Cecil Medicine 26th ed. Philadelphia: Elsevier; 2020. Chp.235.p.1634-1638. 2.Cahill KN, Boyce JA. Urticaria, Angioedema, and Allergic Rhinitis. In: Jameson J, Fauci AS, Kasper DL, Hauser SL, Longo DL, Loscalzo J. eds. Harrison's Principles of Internal Medicine, 20e. McGraw-Hill; 2018. 3. Schwartz LB.Systemic Anaphylaxis, Food Allergy, and Insect Sting Allergy. In: Goldman L, Schafer Andrew I, eds. Goldman-Cecil Medicine 26th ed. Philadelphia: Elsevier; 2020. Chp.238.p.1654-1658. 4. Taylor R. Anaphylaxis. BMJ Best Practice © BMJ Publishing Group Ltd 2021. Last updated: Sep 18, 2020. 5.Ardern-Jones M. Common Cutaneous Drug Reactions. BMJ Best Practice © BMJ Publishing Group Ltd 2020. Last updated: May 20,2020. 6.Grammer LC. Drug Allergy. . In: Goldman L, Schafer Andrew I, eds. Goldman-Cecil Medicine 26th ed. Philadelphia: Elsevier; 2020. Chp.239.p.1658-1660
5 NEPHROLOGY Hypertension. Secondary hypertension. Electrolyte imbalance. Acute renal failure. Cronic renal failure. Acid-base imbalance. DISCUSSION-1 ONCOLOGY Cancer epidemiology and prevention Basic principles in cancer treatment and multidisciplinary approach (1). Basic principles in cancer treatment and multidisciplinary approach (2). Familial and hereditary cancer sendromsBasic principles in cancer diagnosis. Oncological emergencies. Infections and neutropenic fever in cancer patients. Cancer definitions and staging.Cytotoxic chemotherapy and management of toxicities. Targeted therapies and hormonal treatments. Tumor immunology and immunotherapy.
6 NEPHROLOGY Nephrotic syndrome. Glomerulonephritis. Systemic diseases and kidney. National prescribing curriculum (NPC) Discussion-1 by PHARMACOLOGY National prescribing curriculum (NPC) Discussion-2 by PHARMACOLOGY ONCOLOGY Bone and soft tissue tumors. Other cancers;skin, melanoma,CNS tumors. Gynecological cancers Paraneoplastic sendroms Pain management and palliative treatments in cancer patients Lung cancers. Gastrointestinal system cancers. Urological cancers. Breast cancer.
7 CCS403 Final
8 Review of the Semester  
9 Review of the Semester  

 

Course Notes/Textbooks
  1. Maxine Papadakis, Stephen J. McPhee, Michael W. Rabow. CURRENT Medical Diagnosis and Treatment 2016 (LANGE CURRENT Series) 55th Edition 2016
  2. Matthew Stephenson, Joshua Shur, John Black. How to Perform Clinical Procedures: for Medical Students and Junior Doctors, includes 2 DVDs, 2013
  3. Harper’s Illustrated Biochemistry, 30th Ed, Lange. Rodwell VW, Bender DA, Botham RM, Kennelly PJ, Weil PA. 2015.
Suggested Readings/Materials

 

EVALUATION SYSTEM

Semester Activities Number Weigthing
Participation
Laboratory / Application
Field Work
Quizzes / Studio Critiques
Portfolio
1
30
Homework / Assignments
Presentation / Jury
Project
Seminar / Workshop
Oral Exams
1
30
Midterm
Final Exam
1
40
Total

Weighting of Semester Activities on the Final Grade
1
30
Weighting of End-of-Semester Activities on the Final Grade
2
70
Total

ECTS / WORKLOAD TABLE

Semester Activities Number Duration (Hours) Workload
Theoretical Course Hours
(Including exam week: 9 x total hours)
9
14
126
Laboratory / Application Hours
(Including exam week: '.9.' x total hours)
9
16
144
Study Hours Out of Class
9
6
54
Field Work
0
Quizzes / Studio Critiques
0
Portfolio
1
15
15
Homework / Assignments
0
Presentation / Jury
0
Project
0
Seminar / Workshop
0
Oral Exam
1
13
13
Midterms
0
Final Exam
1
25
25
    Total
377

 

COURSE LEARNING OUTCOMES AND PROGRAM QUALIFICATIONS RELATIONSHIP

#
Program Competencies/Outcomes
* Contribution Level
1
2
3
4
5
1

Knowledge for Practice: Uses knowledge in biomedical, clinical, epidemiological, biostatistics, biomedical informatics, social and behavioral sciences for the prevention, diagnosis, treatment and management of medical problems.

X
2

Information Management and Research: Uses the information generated through research and accessed from different sources in evidence-based patient management processes

X
3

Patient management: Provides patient-centered, holistic, safe, reliable and evidence-based health care for common health problems in the community, prioritizing health protection and improvement*.

X
4

Patient and employee safety: Provides health services by considering the health and safety of patients and employees.

X
5

Protection and promotion of health: Prioritizes protecting and improving the health of individuals and society in the provision of health services under usual/unusual situations. Performs clinical and public health practices in a holistic and competent manner

X
6

Adherence to ethical principles: Fulfills the duties and obligations within the framework of ethical principles and, rights and legal responsibilities required by the profession.

X
7

Professional competence: Provides a high-quality healthcare service that prioritizes patient safety. While applying the profession, he/she knows his/her limits, evaluates his/her own performance, determines the aspects that need to be developed and improves them within a plan

X
8

Professional virtues: Avoid behaviors that will undermine the public's trust in medicine. S/he approaches her/his patients with compassion and care without discrimination, and puts their welfare ahead of her/his own interests

9

A healthy physician- a healthy society: Gives importance to his/her personal health, safety and appearance, sets an example for his/her colleagues and society by taking the necessary precautions.

X
10

Planetary health and healthy lifestyles: Considering the effects of the resources offered by our planet on individual and public health, he/she accepts promoting healthy lifestyles and eliminating the factors that negatively affect health his/her duty.

X
11

Protecting and improving health as a social responsibility: Accepts protection and improvement of public health as a social responsibility, identifies the primary health problems of the society served and produces solutions.

12

Health policies: Evaluates the impact of health policies on the health indicators of individuals and society, and advocates increasing the quality of health services.

13

Change management: Systematically identifies and manages the issues/processes and the necessary resources that require change in order to provide quality, safe and cost-effective health care.

14

Personal qualifications: Provides evidence exerting that he/she is equipped enough to lead changes to make healthcare more qualified, safe and cost-effective

X
15

Communication skills: Uses verbal and non-verbal communication effectively. Communicates with patients in a way that makes them feel understood, with active listening behaviors (eye contact, affirmation, summarizing, etc.)

X
16

Communication with patients and their relatives: Establishes supportive relationships with patients and their families that contribute positively to the treatment process

X
17

Communication for qualified and safe health care: Communicates with patients, their relatives, health workers, other professional groups, institutions and organizations in a clear, understandable and professional manner that will minimize patient safety risks and increase the quality of health care. Considers and protects patient privacy and data security in all communications.

X
18

Explains the place and importance of scientific research and evidence in providing qualified and safe health care. Analyzes the health problems in the society s/he serves with scientific methods. Reaches information to access evidence. Uses the information analyzed and the evidence accessed from the literature to provide more qualified and safer health care

X
19

Reflection: Using reflective approaches, he/she questions his/her professional performance, identifies areas that require improvement, and develops his/her professional knowledge and skills by identifying learning needs.

X
20

Stress management: Explains and applies strategies for coping with stress and preventing burnout

X

*1 Lowest, 2 Low, 3 Average, 4 High, 5 Highest

 


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